Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8889377 | 0.92 | LMNA (0.48) | LMNAMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL8889588 | 0.89 | CYP1A2 (0.49) | LMNAMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL8886920 | 0.87 | KMT2A (0.40) | LMNAMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL8889113 | 0.81 | CYP1A2 (0.50) | LMNAMEN1KMT2ASMN1; SMN2PDE4A | |
| SCHEMBL8889460 | 0.80 | MEN1 (0.48) | LMNAMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL8889716 | 0.79 | PDE4A (0.52) | LMNAMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL8887697 | 0.78 | CYP1A2 (0.47) | LMNAMEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL8890203 | 0.78 | CYP1A2 (0.47) | PDE4APDE4BPDE4CPDE4DCYP1A2 | |
| SCHEMBL8886943 | 0.78 | LMNA (0.49) | LMNAMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL8889100 | 0.77 | PTGIR (0.49) | MEN1KMT2APDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997001551-A1 | PYRAZOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-16 | — | — | WO | disclosed |