Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
| ▸ | MAP2K1 | Q02750 | 14/20 | 0.38 |
| ▸ | RAF1 | P04049 | 13/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8889871 | 0.87 | MAP2K1 (0.42) | MAP2K1RAF1CYP3A4CYP2C9KDM4E | |
| SCHEMBL8624288 | 0.70 | HSPD1 (0.39) | ACP1 | |
| SCHEMBL9200704 | 0.68 | CA2 (0.61) | KDM4ECA2 | |
| SCHEMBL963348 | 0.67 | MAP2K1 (0.70) | MAP2K1RAF1CYP3A4CYP2C9HSD17B3 | |
| SCHEMBL19567186 | 0.67 | PTGS1 (0.63) | CA2 | |
| SCHEMBL8617759 | 0.66 | HSPD1 (0.37) | CYP3A4 | |
| SCHEMBL23514767 | 0.65 | CA2 (0.54) | CYP3A4CA2 | |
| SCHEMBL20782066 | 0.65 | CA2 (0.54) | CYP3A4CA2 | |
| SCHEMBL21986566 | 0.65 | CA2 (0.56) | CYP3A4CA2 | |
| SCHEMBL31680271 | 0.65 | CA2 (0.56) | CYP3A4CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5641789-A | INHIBITORS OF LEUKOTRIENES AND/OR BLOCKERS OF LEUKOTRIENE RECEPTORS; USEFUL IN PREVENTION OR TREATMENT OF ASTHMA, ARTHRITIS, PSORIASIS, ULCERS, MYOCARDIAL INFARCTION | PFIZER INC. (US) | 1997-06-24 | — | — | US | disclosed |