Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | SCN4A | P35499 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 9/20 | 0.37 |
| ▸ | PI4KA | P42356 | 9/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 9/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 8/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 8/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 6/20 | 0.37 |
| ▸ | PIP5K1C | O60331 | 5/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.34 |
| ▸ | LIPC | P11150 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL888965 | 0.88 | AAK1 (0.43) | RAB9ANPC1SMN1; SMN2PIK3CAPIK3CD | |
| SCHEMBL12824420 | 0.88 | PGR (0.41) | RAB9ANPC1SCN4ASMN1; SMN2PIK3CA | |
| SCHEMBL12810095 | 0.85 | SMN1; SMN2 (0.47) | RAB9ANPC1SCN4ASMN1; SMN2PIK3CA | |
| SCHEMBL888881 | 0.77 | RAB9A (0.51) | RAB9ANPC1SCN4ASMN1; SMN2PIK3CA | |
| SCHEMBL12824422 | 0.76 | APP (0.43) | RAB9ANPC1SCN4ASMN1; SMN2PIK3CA | |
| SCHEMBL13862834 | 0.76 | APP (0.50) | PIK3CAPI4KAPI4KB | |
| SCHEMBL12810162 | 0.73 | SMN1; SMN2 (0.44) | RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL798519 | 0.73 | RAB9A (0.67) | RAB9ANPC1SCN4ASMN1; SMN2LOXL2 | |
| SCHEMBL12591857 | 0.73 | RAB9A (0.58) | RAB9ANPC1SCN4ASMN1; SMN2LOXL2 | |
| SCHEMBL23308732 | 0.72 | TNF (0.51) | RAB9ANPC1MAPTPAX8NOD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8759332-B2 | Hepatitis C virus inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2014-06-24 | — | — | US | disclosed |
| US-20110064697-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2011-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110064697-A1 | HEPATITIS C VIRUS INHIBITORS | HAVCR2, EIF2AK2, SLC10A1 | RAB9A 3060/4885NPC1 34/4885SCN4A 3949/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.