Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.33 |
| ▸ | LIPC | P11150 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL888945 | 0.88 | RAB9A (0.38) | LOXL2PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL12810162 | 0.85 | SMN1; SMN2 (0.44) | TRPV1MAPTRAB9ATP53SMN1; SMN2 | |
| SCHEMBL888952 | 0.77 | AAK1 (0.52) | AAK1LOXL2PIK3CDPIK3CAPIK3CB | |
| SCHEMBL12810257 | 0.77 | AAK1 (0.52) | AAK1LOXL2PIK3CDPIK3CAPIK3CB | |
| SCHEMBL12824420 | 0.76 | PGR (0.41) | LOXL2PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL12810095 | 0.73 | SMN1; SMN2 (0.47) | PIK3CDPIK3CAPIK3CBPIK3CGMAPT | |
| SCHEMBL888900 | 0.73 | AAK1 (0.46) | AAK1LOXL2PIK3CDPIK3CAPIK3CB | |
| SCHEMBL12810070 | 0.73 | AAK1 (0.46) | AAK1LIPGMAPTRAB9ACASR | |
| SCHEMBL889391 | 0.73 | RAB9A (0.49) | AAK1TRPV1LOXL2HDAC3HDAC1 | |
| SCHEMBL890259 | 0.73 | CASR (0.51) | AAK1TRPV1LOXL2MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8759332-B2 | Hepatitis C virus inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2014-06-24 | — | — | US | disclosed |
| US-20110064697-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2011-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110064697-A1 | HEPATITIS C VIRUS INHIBITORS | HAVCR2, EIF2AK2, SLC10A1 | AAK1 3453/4885TRPV1 2956/4885LOXL2 4423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.