Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8887601 | 0.80 | LMNA (0.48) | MEN1KMT2ASMN1; SMN2HTTNPSR1 | |
| SCHEMBL6825199 | 0.76 | CASR (0.41) | KDM4EALDH1A1PTGDR2ADORA2A | |
| SCHEMBL6822483 | 0.75 | CMKLR1 (0.42) | MEN1KMT2ASMN1; SMN2HTTNPSR1 | |
| SCHEMBL8889377 | 0.74 | LMNA (0.48) | MEN1KMT2ASMN1; SMN2HTTNPSR1 | |
| SCHEMBL3841611 | 0.74 | MAPT (0.70) | MEN1KMT2ASMN1; SMN2HTTNPSR1 | |
| SCHEMBL5150680 | 0.74 | GAA (0.45) | MEN1KMT2AHTTMAPTKDM4E | |
| SCHEMBL5149215 | 0.74 | GAA (0.45) | MEN1KMT2AHTTMAPTKDM4E | |
| SCHEMBL5147948 | 0.73 | HIF1A (0.44) | MEN1KMT2AHTTNPSR1MAPT | |
| SCHEMBL6821959 | 0.73 | ADORA1 (0.42) | PTGDR2 | |
| SCHEMBL5149209 | 0.72 | MAPT (0.45) | MEN1KMT2ASMN1; SMN2HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997001551-A1 | PYRAZOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-16 | — | — | WO | disclosed |