Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 12/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 2/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.48 |
| ▸ | PTAFR | P25105 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891595 | 0.84 | PDE4D (0.67) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL8889809 | 0.83 | PDE4B (0.70) | PDE4DALDH1A1USP2NPSR1L3MBTL1 | |
| SCHEMBL8890700 | 0.83 | ALDH1A1 (0.57) | ALDH1A1USP2NPSR1L3MBTL1PTAFR | |
| SCHEMBL8889603 | 0.82 | ALDH1A1 (0.58) | PDE4DALDH1A1USP2NPSR1L3MBTL1 | |
| SCHEMBL1026961 | 0.82 | PDE4D (1.00) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL1434394 | 0.82 | PDE4D (0.84) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL8554187 | 0.80 | PDE4D (0.73) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL8890105 | 0.79 | PDE4B (0.72) | PDE4DALDH1A1USP2NPSR1L3MBTL1 | |
| SCHEMBL8890126 | 0.78 | PDE4D (0.45) | PDE4DPDE4APDE4BPDE4CPTAFR | |
| SCHEMBL6276143 | 0.78 | ALDH1A1 (0.67) | PDE4DALDH1A1USP2NPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997003967-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND THEIR PHARMACEUTICAL USE | RHONE-POULENC RORER LIMITED (GB) | 1997-02-06 | — | — | WO | claimed |
| WO-1997003967-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND THEIR PHARMACEUTICAL USE | RHONE-POULENC RORER LIMITED (GB) | 1997-02-06 | — | — | WO | disclosed |