Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | OGG1 | O15527 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8888732 | 0.81 | PPARA (0.41) | SLC6A4 | |
| SCHEMBL950050 | 0.80 | PPARG (0.41) | SLC6A4ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL19405290 | 0.78 | OGG1 (0.49) | KMT2AOGG1SLC6A4KDM4EALDH1A1 | |
| SCHEMBL13124486 | 0.76 | SLC6A4 (0.47) | KMT2AOGG1SLC6A4KDM4EALDH1A1 | |
| SCHEMBL8887237 | 0.76 | SLC6A4 (0.47) | KMT2AOGG1SLC6A4KDM4EALDH1A1 | |
| SCHEMBL8890012 | 0.76 | KMT2A (0.44) | KMT2AOGG1SLC6A4KDM4EALDH1A1 | |
| SCHEMBL7214869 | 0.76 | OGG1 (0.54) | KMT2AOGG1SLC6A4KDM4EALDH1A1 | |
| SCHEMBL1500501 | 0.74 | LTA4H (0.43) | SLC6A4L3MBTL1MAPK1 | |
| SCHEMBL5483159 | 0.74 | OGG1 (0.43) | KMT2AOGG1SLC6A4KDM4EALDH1A1 | |
| SCHEMBL5483162 | 0.74 | OGG1 (0.43) | KMT2AOGG1SLC6A4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691340-A | CENTRAL NERVOUS SYSTEM DISORDERS, STROKES, CARDIOVASCULAR DISORDERS, ALZHEIMER*S DISEASE OR ANTIINFLAMMATORY AGENTS | ADIR ET COMPAGNIE (FR) | 1997-11-25 | — | — | US | disclosed |