Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GALR3 | O60755 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1074501 | 0.85 | CTSK (0.49) | CTSKALDH1A1KDM4EMAPK1HPGD | |
| SCHEMBL4498872 | 0.82 | HPGD (0.51) | CTSKALDH1A1KDM4EMAPK1HPGD | |
| SCHEMBL28500929 | 0.82 | ALDH1A1 (0.40) | CTSKALDH1A1KDM4EMAPK1HPGD | |
| SCHEMBL18988308 | 0.80 | KDM4E (0.38) | CTSKALDH1A1KDM4EMAPK1HPGD | |
| SCHEMBL1717600 | 0.80 | HPGD (0.49) | CTSKALDH1A1KDM4EMAPK1HPGD | |
| SCHEMBL8889916 | 0.78 | ALDH1A1 (0.38) | CTSKALDH1A1KDM4EMAPK1HPGD | |
| SCHEMBL31194665 | 0.78 | GAA (0.46) | CTSKALDH1A1KDM4EMAPK1HPGD | |
| SCHEMBL31194470 | 0.77 | HPGD (0.46) | CTSKALDH1A1KDM4EMAPK1HPGD | |
| SCHEMBL7306254 | 0.76 | GAA (0.47) | CTSKALDH1A1KDM4EMAPK1HPGD | |
| SCHEMBL7308000 | 0.76 | LMNA (0.38) | CTSKALDH1A1KDM4EMAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997008149-A1 | SUBSTITUTED 5-AMINOPYRAZOLS AND THEIR USE FOR CONTROLLING ANIMAL PESTS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-03-06 | — | — | WO | disclosed |