Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.50 |
| ▸ | HTR2C | P28335 | 2/20 | 0.50 |
| ▸ | HTR2B | P41595 | 2/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.31 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25882779 | 0.72 | HTR2C (0.68) | HTR2AHTR2CHTR2BMTNR1BMTNR1A | |
| Propane SCHEMBL6328140 | 0.72 | HTR2C (0.60) | HTR2AHTR2CHTR2BMTNR1BMTNR1A | |
| SCHEMBL906000 | 0.70 | HTR2C (0.57) | HTR2AHTR2CHTR2B | |
| SCHEMBL8888059 | 0.70 | HTR2A (0.61) | HTR2AHTR2CHTR2BMTNR1BMTNR1A | |
| SCHEMBL4935456 | 0.70 | HTR2C (0.61) | HTR2AHTR2CHTR2BALDH1A1LMNA | |
| SCHEMBL8890016 | 0.70 | HTR2A (0.61) | HTR2AHTR2CHTR2BMTNR1BMTNR1A | |
| SCHEMBL8888063 | 0.70 | HTR2C (0.65) | HTR2AHTR2CHTR2BMTNR1BMTNR1A | |
| SCHEMBL6328142 | 0.69 | HTR2C (0.56) | HTR2AHTR2CHTR2BMTNR1BMTNR1A | |
| Ammonia Solution, Strong SCHEMBL906002 | 0.69 | HTR2C (0.64) | HTR2AHTR2CHTR2BMTNR1BMTNR1A | |
| SCHEMBL7499133 | 0.68 | HTR2A (0.62) | HTR2AHTR2CHTR2BMTNR1BMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633276-A | MELATONIN SYSTEM DISORDERS | GLAXO GROUP LIMITED (GB) | 1997-05-27 | — | — | US | disclosed |