Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.60 |
| ▸ | HTR2A | P28223 | 6/20 | 0.60 |
| ▸ | HTR2B | P41595 | 5/20 | 0.60 |
| ▸ | MTNR1B | P49286 | 12/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 11/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL906002 | 0.78 | HTR2C (0.64) | HTR2CHTR2AHTR2BMTNR1BMTNR1A | |
| SCHEMBL8888063 | 0.76 | HTR2C (0.65) | HTR2CHTR2AHTR2BMTNR1BMTNR1A | |
| SCHEMBL6328136 | 0.76 | HTR2C (1.00) | HTR2CHTR2AHTR2B | |
| SCHEMBL905999 | 0.76 | HTR2C (1.00) | HTR2CHTR2AHTR2B | |
| SCHEMBL7499133 | 0.74 | HTR2A (0.62) | HTR2CHTR2AHTR2BMTNR1BMTNR1A | |
| SCHEMBL8890016 | 0.73 | HTR2A (0.61) | HTR2CHTR2AHTR2BMTNR1BMTNR1A | |
| SCHEMBL906000 | 0.73 | HTR2C (0.57) | HTR2CHTR2AHTR2B | |
| SCHEMBL4935456 | 0.73 | HTR2C (0.61) | HTR2CHTR2AHTR2B | |
| SCHEMBL8888059 | 0.73 | HTR2A (0.61) | HTR2CHTR2AHTR2BMTNR1BMTNR1A | |
| SCHEMBL8890307 | 0.72 | HTR2A (0.50) | HTR2CHTR2AHTR2BMTNR1BMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6962939-B1 | Condensed indoline derivatives and their use as 5HT, in particular 5HT2C, receptor ligands | VERNALIS RESEARCH LIMITED (GB) | 2005-11-08 | — | — | US | disclosed |