Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
| ▸ | SCN1A | P35498 | 1/20 | 0.30 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.30 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892498 | 0.93 | PTGDR2 (0.33) | PTGDR2PDE2AGPBAR1POLBTAS1R3 | |
| SCHEMBL8890261 | 0.90 | DHODH (0.33) | PDE2ANAMPTTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL8891669 | 0.85 | ADRA1D (0.35) | PTGDR2GPBAR1POLBTAS1R3TAS1R1 | |
| SCHEMBL8891112 | 0.85 | TAS1R3 (0.35) | PDE2ANAMPTTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL8891457 | 0.85 | NR1H4 (0.35) | PTGDR2TAS1R3TAS1R1TAS1R2NPC1 | |
| SCHEMBL8889886 | 0.84 | HPGD (0.36) | PTGDR2GPBAR1POLBTAS1R3TAS1R1 | |
| SCHEMBL8899416 | 0.83 | DHODH (0.32) | PTGDR2PDE2ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL8889996 | 0.83 | SLC6A2 (0.32) | PDE2ANAMPTTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL7627829 | 0.83 | DHODH (0.34) | PDE2ANAMPTGPBAR1TAS1R3TAS1R1 | |
| SCHEMBL8891512 | 0.82 | HPGD (0.36) | PTGDR2ALDH1A1HTTSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997028136-A1 | BENZOYLISOXAZOLES AND 2-CYANO-1,3-DIONE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-07 | — | — | WO | disclosed |