Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SCN1A | P35498 | 2/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.32 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 2/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890374 | 0.92 | CCR5 (0.36) | NAMPTALDH1A1TSHRSCN1ASCN2A | |
| SCHEMBL8488431 | 0.86 | DHODH (0.34) | NAMPTPDE2ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL27295039 | 0.84 | DHODH (0.33) | NAMPTPDE2ADHODHEPHX2 | |
| SCHEMBL8891642 | 0.84 | ALDH1A1 (0.39) | PTGS1PTGS2ALDH1A1MEN1KMT2A | |
| SCHEMBL8893348 | 0.84 | ALDH1A1 (0.43) | ALDH1A1TSHRMEN1KMT2ASCN1A | |
| SCHEMBL8890372 | 0.83 | FFAR4 (0.36) | SCN1ASCN2ASCN3APOLBCCR5 | |
| SCHEMBL8892076 | 0.83 | KDM4E (0.34) | NAMPTALDH1A1TSHRKMT2APOLB | |
| SCHEMBL8890902 | 0.83 | RAB9A (0.39) | ALDH1A1MEN1KMT2ASCN1ASCN2A | |
| SCHEMBL8890001 | 0.83 | KDM4E (0.36) | NAMPTALDH1A1TSHRKMT2AEPHX2 | |
| SCHEMBL8889606 | 0.82 | TSHR (0.34) | NAMPTALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997028136-A1 | BENZOYLISOXAZOLES AND 2-CYANO-1,3-DIONE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-07 | — | — | WO | disclosed |