Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RAF1 | P04049 | 2/20 | 0.37 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891956 | 0.83 | HPGD (0.40) | ALDH1A1KDM4EHPGDGAAF10 | |
| SCHEMBL8890380 | 0.82 | PDE4D (0.41) | ALDH1A1KDM4EHPGDGAAF10 | |
| SCHEMBL8890131 | 0.74 | PDE4A (0.43) | ALDH1A1PDE4DKMT2APDE4APDE4B | |
| SCHEMBL8891595 | 0.72 | PDE4D (0.67) | F10PDE4DRAF1MAP2K1PDE4A | |
| SCHEMBL8891655 | 0.72 | PDE4B (0.70) | F10PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL6583680 | 0.70 | PDE4B (0.42) | ALDH1A1KDM4EF10TDP1PDE4D | |
| SCHEMBL14164834 | 0.70 | PPARG (0.49) | TDP1PDE4DSMN1; SMN2KMT2APDE4A | |
| SCHEMBL14164953 | 0.70 | PPARG (0.49) | TDP1PDE4DSMN1; SMN2KMT2APDE4A | |
| SCHEMBL6424862 | 0.70 | S1PR1 (0.42) | ALDH1A1PDE4DSMN1; SMN2PDE4APDE4B | |
| SCHEMBL8890013 | 0.69 | KDM4E (0.61) | ALDH1A1KDM4EF10TDP1PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997003967-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND THEIR PHARMACEUTICAL USE | RHONE-POULENC RORER LIMITED (GB) | 1997-02-06 | — | — | WO | claimed |