Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.32 |
| ▸ | F3 | P13726 | 1/20 | 0.32 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.31 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6999207 | 0.73 | AMY1A (0.48) | AMY1ARAB9ASMN1; SMN2S1PR4KDM4E | |
| SCHEMBL8822124 | 0.72 | TLR2 (0.36) | POLBS1PR4CYP19A1CNR1ACHE | |
| SCHEMBL8822128 | 0.71 | AMY1A (0.46) | AMY1APOLBRAB9AS1PR4F7 | |
| SCHEMBL9549749 | 0.70 | IDO1 (0.49) | POLBRAB9ASMN1; SMN2 | |
| SCHEMBL30599160 | 0.70 | ALDH1A1 (0.41) | POLBHPGDRAB9ASMN1; SMN2RIPK1 | |
| SCHEMBL1923172 | 0.65 | ALDH1A1 (0.37) | POLBHPGDRAB9ASMN1; SMN2RIPK1 | |
| SCHEMBL8540776 | 0.64 | AMY1A (0.48) | AMY1ARAB9AS1PR4KDM4ENPBWR1 | |
| SCHEMBL31463535 | 0.64 | AMY1A (0.48) | AMY1ARAB9AS1PR4KDM4ENPBWR1 | |
| SCHEMBL7435141 | 0.64 | ALDH1A1 (0.33) | POLBHPGDRAB9ASMN1; SMN2RIPK1 | |
| SCHEMBL31345017 | 0.63 | S1PR4 (0.40) | AMY1ASMN1; SMN2S1PR4KCNJ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997031917-A1 | SUBSTITUTED PHENYLOXAZOLIDINONES AND THEIR USE AS ANTIBIOTICS | ZENECA LIMITED (GB) | 1997-09-04 | — | — | WO | disclosed |