Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.47 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22605719 | 0.83 | HTR6 (0.47) | HTR6CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL8902683 | 0.80 | CHRM2 (0.42) | CHRM1CHRM2CHRM4CHRM3OPRM1 | |
| SCHEMBL31152738 | 0.78 | HTR6 (0.50) | HTR6CHRM2OPRM1ALDH1A1 | |
| SCHEMBL28512511 | 0.73 | OPRM1 (0.43) | CHRM1CHRM2CHRM4CHRM3OPRM1 | |
| SCHEMBL28514062 | 0.72 | OPRM1 (0.39) | HTR6CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL22869704 | 0.72 | HSD11B1 (0.52) | ALDH1A1CYP3A4CYP2C19SMN1; SMN2MAPK1 | |
| SCHEMBL28497378 | 0.72 | CHRM1 (0.42) | HTR6CHRM1CHRM2CHRM4OPRM1 | |
| SCHEMBL4306275 | 0.72 | CHRM1 (0.57) | CHRM1OPRM1OPRL1DRD2KCNH2 | |
| SCHEMBL3243793 | 0.72 | HSD11B1 (0.53) | CHRM1CHRM2CHRM4CHRM3OPRM1 | |
| SCHEMBL3243652 | 0.72 | OPRM1 (0.62) | CHRM1OPRM1OPRK1OPRD1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997016187-A1 | MUSCARINE ANTAGONISTS | MERCK & CO., INC. (US) | 1997-05-09 | — | — | WO | disclosed |