Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GALR2 | O43603 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GLP1R | P43220 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 9/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891980 | 0.88 | POLB (0.46) | PGK1POLBGALR2LMNAGLP1R | |
| SCHEMBL8891038 | 0.85 | POLB (0.43) | PGK1POLBGALR2LMNAGLP1R | |
| SCHEMBL8891287 | 0.83 | POLB (0.40) | PGK1POLBGALR2LMNAGLP1R | |
| SCHEMBL8900822 | 0.79 | GUCY1B2 (0.48) | PGK1POLBLMNARXFP1KDM4E | |
| SCHEMBL5722727 | 0.78 | POLB (0.44) | PGK1POLBGALR2LMNAALDH1A1 | |
| SCHEMBL8892461 | 0.76 | RXFP1 (0.48) | POLBLMNARXFP1KDM4EMEN1 | |
| SCHEMBL8893491 | 0.74 | PGK1 (0.59) | PGK1POLBGALR2LMNAGLP1R | |
| SCHEMBL8893038 | 0.73 | POLB (0.47) | PGK1POLBGALR2LMNAGLP1R | |
| SCHEMBL8891354 | 0.71 | GUCY1B2 (0.45) | PGK1POLBLMNARXFP1KDM4E | |
| SCHEMBL3578944 | 0.71 | RXFP1 (0.62) | POLBLMNARXFP1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997032858-A1 | QUINOXALINE DERIVATIVES AS GLUTAMATE RECEPTOR ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-12 | — | — | WO | disclosed |