Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | GALR2 | O43603 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PGK1 | P00558 | 1/20 | 0.45 |
| ▸ | GLP1R | P43220 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893491 | 0.88 | PGK1 (0.59) | POLBGALR2LMNAPGK1GLP1R | |
| SCHEMBL8891980 | 0.86 | POLB (0.46) | POLBGALR2LMNAPGK1GLP1R | |
| SCHEMBL8891999 | 0.84 | POLB (0.43) | POLBGALR2LMNAPGK1GLP1R | |
| SCHEMBL8892839 | 0.84 | PGK1 (0.45) | POLBGALR2LMNAPGK1GLP1R | |
| SCHEMBL8556955 | 0.81 | GAA (0.51) | POLBGALR2LMNAPGK1ALDH1A1 | |
| SCHEMBL8891651 | 0.80 | LMNA (0.40) | POLBGALR2LMNAPGK1GLP1R | |
| SCHEMBL8892306 | 0.79 | GUCY1B2 (0.50) | POLBLMNARXFP1ALDH1A1L3MBTL1 | |
| SCHEMBL8892240 | 0.78 | PDE7A (0.51) | POLBGALR2LMNAPGK1GLP1R | |
| Hydrochloric Acid SCHEMBL8891535 | 0.77 | LMNA (0.44) | POLBLMNAALDH1A1L3MBTL1GAA | |
| SCHEMBL8892065 | 0.77 | PGK1 (0.39) | POLBGALR2LMNAPGK1GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997032858-A1 | QUINOXALINE DERIVATIVES AS GLUTAMATE RECEPTOR ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-12 | — | — | WO | disclosed |