Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.79 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.79 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.79 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.79 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.79 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.79 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.79 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.79 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.79 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.79 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | CCR3 | P51677 | 3/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5999857 | 0.84 | MEN1 (0.64) | GRIN2DGRIN3BADRA1DADRA1AADRA1B | |
| SCHEMBL31212416 | 0.81 | KMT2A (0.79) | MEN1KMT2AALDH1A1CCR3 | |
| Hydrochloric Acid SCHEMBL8934366 | 0.80 | SLC6A4 (0.61) | MEN1KMT2AKDM4EALDH1A1SLC6A4 | |
| SCHEMBL4023997 | 0.79 | GRIN2B (0.66) | GRIN2DGRIN3BADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL7406256 | 0.78 | CCR3 (0.79) | KDM4EALDH1A1MAPTCCR3 | |
| Hydrochloric Acid SCHEMBL1373308 | 0.78 | GRIN2D (0.64) | GRIN2DGRIN3BADRA1DADRA1AADRA1B | |
| SCHEMBL28294049 | 0.78 | SIGMAR1 (0.60) | SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL9053025 | 0.77 | GRIN2D (0.63) | GRIN2DGRIN3BADRA1DADRA1AADRA1B | |
| SCHEMBL4281407 | 0.76 | GAA (0.64) | GRIN2DGRIN3BADRA1DADRA1AADRA1B | |
| SCHEMBL15857848 | 0.76 | GRIN1 (0.63) | GRIN2DGRIN3BADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997009310-A1 | 1-PHENYL-3-4-[BENZYLPIPERIDINYL-1]-PROPANOL-1 DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL APPLICATION THEREOF | SYNTHELABO (FR) | 1997-03-13 | — | — | WO | disclosed |