SCHEMBL4023997

SCHEMBL4023997

O=C(O)CN1CCC(Cc2ccccc2)CC1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2B Q13224 2/20 0.66
GRIN2D O15399 1/20 0.66
GRIN3B O60391 1/20 0.66
ADRA1D P25100 1/20 0.66
ADRA1A P35348 1/20 0.66
ADRA1B P35368 1/20 0.66
GRIN1 Q05586 1/20 0.66
GRIN2A Q12879 1/20 0.66
GRIN2C Q14957 1/20 0.66
GRIN3A Q8TCU5 1/20 0.66
CCR3 P51677 2/20 0.65
ACHE P22303 1/20 0.63
KDM4E B2RXH2 1/20 0.61
MEN1 O00255 1/20 0.60
ALDH1A1 P00352 1/20 0.60
LMNA P02545 1/20 0.60
HTT P42858 1/20 0.60
KMT2A Q03164 1/20 0.60
SMN1; SMN2 Q16637 1/20 0.60
GAA P10253 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1373308 0.98 GRIN2D (0.64) GRIN2BGRIN2DGRIN3BADRA1DADRA1A
SCHEMBL5233388 0.91 MEN1 (0.61) GRIN2BGRIN2DGRIN3BADRA1DADRA1A
SCHEMBL19382678 0.91 GRIN2D (0.56) GRIN2BGRIN2DGRIN3BADRA1DADRA1A
SCHEMBL8485320 0.91 GRIN2D (0.56) GRIN2BGRIN2DGRIN3BADRA1DADRA1A
SCHEMBL15857848 0.87 GRIN1 (0.63) GRIN2BGRIN2DGRIN3BADRA1DADRA1A
SCHEMBL4281407 0.87 GAA (0.64) GRIN2BGRIN2DGRIN3BADRA1DADRA1A
Lithium Ion SCHEMBL25243064 0.86 GRIN2D (0.61) GRIN2BGRIN2DGRIN3BADRA1DADRA1A
SCHEMBL5206098 0.86 OPRM1 (0.56) GRIN2BGRIN2DGRIN3BADRA1DADRA1A
SCHEMBL5999857 0.86 MEN1 (0.64) GRIN2BGRIN2DGRIN3BADRA1DADRA1A
SCHEMBL6001210 0.84 MEN1 (0.53) GRIN2BGRIN2DGRIN3BADRA1DADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260076982-A1 Prodrugs of Cannbidiol [CBD]-Type Phytocannabinoids and a Process for Preparation Thereof COUNCIL SCIENT IND RES (IN) 2026-03-19 US disclosed
EP-4551241-A1 PRODRUGS OF CANNBIDIOL [CBD]-TYPE PHYTOCANNABINOIDS AND A PROCESS FOR PREPARATION THEREOF Council of Scientific & Industrial Research (IN) 2025-05-14 EP disclosed
WO-2024009324-A1 PRODRUGS OF CANNBIDIOL [CBD]-TYPE PHYTOCANNABINOIDS AND A PROCESS FOR PREPARATION THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2024-01-11 WO disclosed
WO-2024009324-A1 PRODRUGS OF CANNBIDIOL [CBD]-TYPE PHYTOCANNABINOIDS AND A PROCESS FOR PREPARATION THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2024-01-11 WO disclosed
US-20230212144-A1 5-MEMBERED HETEROARYL DERIVATIVE CONTAINING AT LEAST ONE N, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING MENTAL DISORDERS, CONTAINING SAME AS ACTIVE INGREDIENT TRINEURO (KR) 2023-07-06 US disclosed
EP-1513811-B1 NON-PEPTIDIC BRS-3 AGONISTS SOLVAY PHARM GMBH (DE) 2009-04-08 EP disclosed
EP-1565453-A4 2- (4-BENZYL)-1-PIPERIDINYL)METHYL|BENZIMIDAZOLE-5-OL DERIVATIVES AS NR2B RECEPTOR ANTAGONISTS MERCK & CO INC (US) 2007-10-10 EP disclosed
US-7244743-B2 Non-peptidic BRS-3 agonists SOLVAY PHARMACEUTICALS GMBH (DE) 2007-07-17 US disclosed
US-20060160853-A1 2-[(4-Benzyl)-1-piperidinyl)methyl]benzimidazole-5-ol derivatives as nr2b receptor antagonists MERCK & CO., INC. 2006-07-20 US disclosed
EP-1565453-A1 2- (4-BENZYL)-1-PIPERIDINYL)METHYL]BENZIMIDAZOLE-5-OL DERIVATIVES AS NR2B RECEPTOR ANTAGONISTS Merck & Co., Inc. (US) 2005-08-24 EP disclosed
US-20050171146-A1 Non-peptidic BRS-3 agonists SOLVAY PHARMACEUTICALS GMBH (DE) 2005-08-04 US disclosed
EP-1513811-A1 NON-PEPTIDIC BRS-3 AGONISTS Solvay Pharmaceuticals GmbH (DE) 2005-03-16 EP disclosed
WO-2004048364-A1 2-[(4-BENZYL)-1-PIPERIDINYL)METHYL]BENZIMIDAZOLE-5-OL DERIVATIVES AS NR2B RECEPTOR ANTAGONISTS MERCK & CO., INC. (US) 2004-06-10 WO disclosed
WO-2003104196-A1 NON-PEPTIDIC BRS-3 AGONISTS SOLVAY PHARMACEUTICALS GMBH (DE) 2003-12-18 WO disclosed
US-6642256-B2 Brain disorders, psychological disorders, antiischemic agents, central nervous system disorders WARNER-LAMBERT COMPANY LLC 2003-11-04 US disclosed
EP-1345935-A2 PIPERIDINE DERIVATIVES AS SUBTYPE SELECTIVE N-METHYL-D-ASPARTATE ANTAGONISTS Warner-Lambert Company LLC (US) 2003-09-24 EP disclosed
US-20030018021-A1 Piperidine derivatives as subtype selective N-methyl-D-aspartate antagonists KORNBERG BRIAN EDWARD (US) 2003-01-23 US disclosed
WO-2002050070-A2 PIPERIDINE DERIVATIVES AS SUBTYPE SELECTIVE N-METHYL-D-ASPARTATE ANTAGONISTS WARNER-LAMBERT COMPANY LLC (US) 2002-06-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260076982-A1 Prodrugs of Cannbidiol [CBD]-Type Phytocannabinoids and a Process for Preparation Thereof CNR1, CNR2, CBR1 GRIN2B 799/4885GRIN2D 1187/4885GRIN3B 1589/4885
US-20060160853-A1 2-[(4-Benzyl)-1-piperidinyl)methyl]benzimidazole-5-ol derivatives as nr2b receptor antagonists GRIN2B, GRIN1, GRIN2A GRIN2B 1/4885GRIN2D 7/4885GRIN3B 4/4885
US-20230212144-A1 5-MEMBERED HETEROARYL DERIVATIVE CONTAINING AT LEAST ONE N, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING MENTAL DISORDERS, CONTAINING SAME AS ACTIVE INGREDIENT HTR5A, HTR2C, TPH1 GRIN2B 149/4885GRIN2D 82/4885GRIN3B 154/4885
US-20050171146-A1 Non-peptidic BRS-3 agonists BRS3, NPR3, ADRB3 GRIN2B 325/4885GRIN2D 774/4885GRIN3B 160/4885
US-20030018021-A1 Piperidine derivatives as subtype selective N-methyl-D-aspartate antagonists GRIN1, OPRD1, OPRM1 GRIN2B 5/4885GRIN2D 9/4885GRIN3B 10/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.