Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | BACE1 | P56817 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7501904 | 0.84 | DRD2 (0.63) | SIGMAR1BCHEACHEDRD2DRD4 | |
| SCHEMBL7695896 | 0.80 | LTA4H (0.65) | BCHEACHE | |
| Fumaric Acid SCHEMBL8555260 | 0.79 | — | — | |
| Maleic Acid SCHEMBL8555257 | 0.79 | — | — | |
| SCHEMBL8100648 | 0.78 | SIGMAR1 (0.52) | SIGMAR1BCHEACHEBACE1 | |
| SCHEMBL23182609 | 0.78 | ACHE (0.56) | BCHEACHE | |
| SCHEMBL7676115 | 0.78 | ACHE (0.56) | BCHEACHE | |
| SCHEMBL8890620 | 0.78 | GRIN2D (0.79) | SLC6A4SLC6A3 | |
| SCHEMBL7374621 | 0.77 | SIGMAR1 (0.69) | SIGMAR1BCHEACHEBACE1 | |
| SCHEMBL6993451 | 0.77 | SIGMAR1 (0.67) | SIGMAR1DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109743875-B | Inhibitors of the MENIN-MLL interaction | 生命医药有限责任公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-109743875-A | The inhibitor of MENIN-MLL interaction | 生命医药公司 | 2019-05-10 | — | — | CN | disclosed |