Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.39 |
| ▸ | CNR1 | P21554 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PPIA | P62937 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.34 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.34 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893572 | 0.90 | CNR2 (0.40) | CNR2CNR1LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL8890386 | 0.89 | LMNA (0.35) | CNR2CNR1LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL8893466 | 0.89 | LMNA (0.47) | CNR2CNR1LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL8891639 | 0.88 | ALDH1A1 (0.48) | CNR2CNR1LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL8891686 | 0.87 | ALDH1A1 (0.40) | CNR2CNR1LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL8891800 | 0.83 | LMNA (0.36) | LMNAMAPK1SMN1; SMN2ALDH1A1PKM | |
| SCHEMBL8890057 | 0.81 | NPC1 (0.37) | LMNAMAPK1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL8891240 | 0.81 | ABCC9 (0.35) | LMNASMN1; SMN2ALDH1A1POLBABCC9 | |
| SCHEMBL8891419 | 0.80 | ALDH1A1 (0.36) | CNR2LMNAMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8891905 | 0.80 | LMNA (0.48) | CNR2CNR1LMNAMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607976-A | ANNTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |