Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | RARB | P10826 | 5/20 | 0.47 |
| ▸ | RARA | P10276 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8417581 | 0.85 | MAPT (0.52) | RAB9AMAPTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL7933637 | 0.85 | RAB9A (0.54) | RAB9AMAPTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL8883086 | 0.85 | RAB9A (0.54) | RAB9AMAPTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL8881686 | 0.83 | CASP3 (0.52) | RAB9AMAPTALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL8415817 | 0.81 | RAB9A (0.50) | RAB9AMAPTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL6418550 | 0.79 | HSD17B10 (0.57) | RAB9AMAPTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL8545371 | 0.79 | KDM4E (0.59) | RAB9AMAPTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL8884801 | 0.79 | KDM4E (0.59) | RAB9AMAPTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL8769157 | 0.79 | KDM4E (0.59) | RAB9AMAPTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL14703081 | 0.78 | HSD17B10 (0.56) | RAB9AMAPTKDM4EHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5595685-A | THIAZOLE DERIVATIVE | CANON KABUSHIKI KAISHA (JP) | 1997-01-21 | — | — | US | disclosed |
| EP-0439170-B1 | Mesomorphic compound, liquid crystal composition containing same, liquid crystal device using same and display apparatus | CANON KK (JP) | 1995-04-19 | — | — | EP | disclosed |
| EP-0439170-A2 | Mesomorphic compound, liquid crystal composition containing same, liquid crystal device using same and display apparatus | CANON KABUSHIKI KAISHA (JP) | 1991-07-31 | — | — | EP | disclosed |