SCHEMBL8417581

SCHEMBL8417581

CCCCCCCCCCc1ncc(-c2ccc(O)cc2)s1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.52
RAB9A P51151 3/20 0.52
SMN1; SMN2 Q16637 3/20 0.52
NPC1 O15118 2/20 0.52
STAT3 P40763 1/20 0.52
ATM Q13315 1/20 0.52
ALDH1A1 P00352 4/20 0.47
ESR1 P03372 3/20 0.47
ADRA2A P08913 2/20 0.47
ADORA3 P0DMS8 2/20 0.47
TACR2 P21452 2/20 0.47
SLC6A2 P23975 2/20 0.47
SLC6A4 P31645 2/20 0.47
SLC6A3 Q01959 2/20 0.47
TP53 P04637 2/20 0.47
CYP3A4 P08684 2/20 0.47
KDM4E B2RXH2 2/20 0.47
HSD17B10 Q99714 2/20 0.47
LMNA P02545 1/20 0.47
SHBG P04278 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8211108 0.87 MAPT (0.43) MAPTRAB9ASMN1; SMN2NPC1STAT3
SCHEMBL8890941 0.85 RAB9A (0.51) MAPTRAB9ASMN1; SMN2NPC1STAT3
SCHEMBL8881686 0.83 CASP3 (0.52) MAPTRAB9ASMN1; SMN2NPC1ALDH1A1
SCHEMBL8769157 0.82 KDM4E (0.59) MAPTRAB9ASMN1; SMN2NPC1STAT3
SCHEMBL8545371 0.82 KDM4E (0.59) MAPTRAB9ASMN1; SMN2NPC1STAT3
SCHEMBL8884801 0.82 KDM4E (0.59) MAPTRAB9ASMN1; SMN2NPC1STAT3
SCHEMBL8883196 0.79 KMT2A (0.46) MAPTRAB9ASMN1; SMN2NPC1ALDH1A1
SCHEMBL8883866 0.79 KMT2A (0.46) MAPTRAB9ASMN1; SMN2NPC1ALDH1A1
SCHEMBL8769170 0.75 HSD17B1 (0.55) MAPTRAB9ASMN1; SMN2NPC1STAT3
SCHEMBL8882165 0.75 ALDH1A1 (0.43) MAPTRAB9ASMN1; SMN2NPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0625513-B1 Mesomorphic compound, liquid crystal composition containing it, liquid crystal device using the composition, display apparatus and method CANON KK (JP) 1999-09-22 EP disclosed
US-5595685-A THIAZOLE DERIVATIVE CANON KABUSHIKI KAISHA (JP) 1997-01-21 US disclosed
US-5580488-A DISPOSING LIQUID CRYSTAL COMPOSITION BETWEEN A PAIR OF ELECTRODE PLATES CANON KABUSHIKI KAISHA (JP) 1996-12-03 US disclosed
EP-0439170-B1 Mesomorphic compound, liquid crystal composition containing same, liquid crystal device using same and display apparatus CANON KK (JP) 1995-04-19 EP disclosed
EP-0625513-A1 Mesomorphic compound, liquid crystal composition containing it, liquid crystal device using the composition, display apparatus and method CANON KABUSHIKI KAISHA (JP) 1994-11-23 EP disclosed
EP-0439170-A2 Mesomorphic compound, liquid crystal composition containing same, liquid crystal device using same and display apparatus CANON KABUSHIKI KAISHA (JP) 1991-07-31 EP disclosed