Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 1.00 |
| ▸ | PPARG | P37231 | 1/20 | 1.00 |
| ▸ | NCOA2 | Q15596 | 1/20 | 1.00 |
| ▸ | IKBKB | O14920 | 9/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.46 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL167906 | 0.80 | IKBKB (0.69) | KDM4EHSD17B10PPARGNCOA2IKBKB | |
| SCHEMBL31061359 | 0.78 | IKBKB (1.00) | KDM4EHSD17B10PPARGNCOA2IKBKB | |
| SCHEMBL3124862 | 0.78 | IKBKB (0.71) | KDM4EHSD17B10PPARGNCOA2IKBKB | |
| SCHEMBL8890199 | 0.75 | IKBKB (0.61) | KDM4EHSD17B10PPARGNCOA2IKBKB | |
| SCHEMBL3124515 | 0.74 | IKBKB (0.65) | KDM4EHSD17B10PPARGNCOA2IKBKB | |
| SCHEMBL31198739 | 0.73 | IKBKB (0.63) | KDM4EHSD17B10PPARGNCOA2IKBKB | |
| SCHEMBL4741742 | 0.71 | IKBKB (0.57) | KDM4EHSD17B10PPARGNCOA2IKBKB | |
| SCHEMBL3127593 | 0.71 | IKBKB (0.67) | KDM4EHSD17B10PPARGNCOA2IKBKB | |
| SCHEMBL5013672 | 0.70 | GAA (0.68) | KDM4EHSD17B10PPARGNCOA2IKBKB | |
| SCHEMBL2179708 | 0.69 | TARBP2 (0.64) | KDM4EHSD17B10PPARGNCOA2IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997024340-A1 | OXAZOLE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-07-10 | — | — | WO | disclosed |