Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 2/20 | 0.32 |
| ▸ | TYK2 | P29597 | 2/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890226 | 0.90 | NR3C1 (0.35) | NAAADHODHTYK2PTGDR2JAK2 | |
| SCHEMBL8890477 | 0.90 | NR3C1 (0.38) | DHODHTYK2CYP3A4JAK2JAK1 | |
| SCHEMBL8891108 | 0.89 | NR3C1 (0.32) | DHODHTYK2CYP3A4JAK2JAK1 | |
| SCHEMBL8891898 | 0.89 | DHODH (0.41) | DHODHPTGDR2CACNA1BNR1I2 | |
| SCHEMBL8891351 | 0.89 | EPHX2 (0.36) | P2RX7PTGDR2CYP3A4NR3C1LMNA | |
| SCHEMBL8890787 | 0.86 | DHODH (0.43) | DHODHCACNA1B | |
| SCHEMBL8891637 | 0.84 | LMNA (0.34) | DHODHTYK2CACNA1BCYP3A4JAK2 | |
| SCHEMBL8891093 | 0.84 | NR3C1 (0.34) | DHODHTYK2P2RX7PTGDR2CACNA1B | |
| SCHEMBL8889540 | 0.83 | DHODH (0.32) | DHODHCYP3A4PTGS1PTGS2 | |
| SCHEMBL8890982 | 0.83 | LMNA (0.34) | DHODHTYK2P2RX7PTGDR2JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997028136-A1 | BENZOYLISOXAZOLES AND 2-CYANO-1,3-DIONE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-07 | — | — | WO | disclosed |