Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.33 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.33 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | CCR2 | P41597 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891767 | 0.91 | KDM4E (0.34) | KDM4EOPRM1OPRD1ALDH1A1GAA | |
| SCHEMBL8891256 | 0.89 | KDM4E (0.34) | KDM4EOPRM1OPRD1ALDH1A1ABCC9 | |
| SCHEMBL8891410 | 0.88 | KDM4E (0.41) | KDM4EOPRM1OPRD1ALDH1A1ABCC9 | |
| SCHEMBL8891401 | 0.86 | ABCC9 (0.47) | KDM4EALDH1A1ABCC9ABCC8KCNJ11 | |
| SCHEMBL8891006 | 0.85 | LMNA (0.42) | KDM4EALDH1A1ABCC9ABCC8KCNJ11 | |
| SCHEMBL8890579 | 0.85 | ABCC9 (0.32) | ABCC9ABCC8KCNJ11GAAKMT2A | |
| SCHEMBL8890673 | 0.84 | NPSR1 (0.43) | KDM4EALDH1A1ABCC9ABCC8KCNJ11 | |
| SCHEMBL8890794 | 0.83 | ABCC9 (0.32) | ABCC9ABCC8KCNJ11GAAKMT2A | |
| SCHEMBL8892035 | 0.83 | LMNA (0.33) | ALDH1A1ABCC9ABCC8KCNJ11LMNA | |
| SCHEMBL8891719 | 0.82 | ABCC9 (0.32) | ABCC9ABCC8KCNJ11GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607976-A | ANNTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |