Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.33 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.33 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 4/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893666 | 0.91 | KDM4E (0.35) | KDM4EOPRM1OPRD1TP53CA2 | |
| SCHEMBL8891172 | 0.89 | KDM4E (0.33) | KDM4EOPRM1OPRD1ABCC9ABCC8 | |
| SCHEMBL8891448 | 0.88 | KDM4E (0.42) | KDM4EOPRM1OPRD1ABCC9ABCC8 | |
| SCHEMBL8891815 | 0.85 | ABCC9 (0.48) | ABCC9ABCC8KCNJ11GAAKMT2A | |
| SCHEMBL8893730 | 0.85 | HTT (0.34) | KDM4EABCC9ABCC8KCNJ11CA2 | |
| SCHEMBL8891687 | 0.84 | LMNA (0.43) | KDM4EABCC9ABCC8KCNJ11GAA | |
| SCHEMBL8892350 | 0.83 | ABCC9 (0.33) | ABCC9ABCC8KCNJ11CA2GAA | |
| SCHEMBL8894341 | 0.83 | L3MBTL1 (0.42) | ABCC9ABCC8KCNJ11TP53CA2 | |
| SCHEMBL8894254 | 0.82 | NPSR1 (0.44) | KDM4EABCC9ABCC8KCNJ11GAA | |
| SCHEMBL8891787 | 0.82 | HTT (0.35) | KDM4EABCC9ABCC8KCNJ11CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607976-A | ANNTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |