Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 3/20 | 0.44 |
| ▸ | CASP2 | P42575 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ICMT | O60725 | 1/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17453102 | 0.96 | DNM1 (0.47) | MCL1DNM1FAAHCASP2CNR1 | |
| SCHEMBL16995712 | 0.93 | MCL1 (0.43) | MCL1DNM1FAAHCASP2CNR1 | |
| SCHEMBL24436199 | 0.91 | MCL1 (0.42) | MCL1DNM1FAAHCASP2CNR1 | |
| SCHEMBL889191 | 0.90 | DNM1 (0.49) | MCL1DNM1FAAHCASP2CNR1 | |
| SCHEMBL19726631 | 0.90 | DNM1 (0.49) | MCL1DNM1FAAHCASP2CNR1 | |
| SCHEMBL16995711 | 0.89 | DNM1 (0.42) | MCL1DNM1FAAHCASP2CNR1 | |
| SCHEMBL17453099 | 0.89 | DNM1 (0.42) | MCL1DNM1FAAHCASP2CNR1 | |
| SCHEMBL18346555 | 0.89 | DNM1 (0.42) | MCL1DNM1FAAHCASP2CNR1 | |
| SCHEMBL16995716 | 0.89 | DNM1 (0.42) | MCL1DNM1FAAHCASP2CNR1 | |
| SCHEMBL17453156 | 0.89 | DNM1 (0.42) | MCL1DNM1FAAHCASP2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170312363-A1 | MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2017-11-02 | — | — | US | disclosed |
| US-20160015823-A1 | PEPTIDE-DENDRIMER CONJUGATES AND USES THEREOF | ANGIOCHEM INC. (CA) | 2016-01-21 | — | — | US | disclosed |
| US-20120009222-A1 | MODULATION OF THE IMMUNE RESPONSE | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120009222-A1 | MODULATION OF THE IMMUNE RESPONSE | FCGRT, MYD88, C3AR1 | MCL1 1122/4885DNM1 4279/4885FAAH 858/4885 |
| US-20160015823-A1 | PEPTIDE-DENDRIMER CONJUGATES AND USES THEREOF | LRP6, LDLR, SELPLG | MCL1 381/4885DNM1 139/4885FAAH 4561/4885 |
| US-20170312363-A1 | MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR | HDGF, F11, F12 | MCL1 2299/4885DNM1 2280/4885FAAH 1494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.