Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891351 | 0.92 | EPHX2 (0.36) | PTGDR2KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL8890477 | 0.90 | NR3C1 (0.38) | CYP1A2CYP3A4CYP2D6CYP2C19EPHX2 | |
| SCHEMBL8901109 | 0.86 | P2RX7 (0.32) | PTGDR2 | |
| SCHEMBL8891528 | 0.85 | PTGDR2 (0.36) | PTGDR2EPHX2RAB9AGPBAR1POLB | |
| SCHEMBL8891637 | 0.84 | LMNA (0.34) | KMT2AMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8890152 | 0.84 | LMNA (0.36) | EPHX2F10NR3C1CDK2LMNA | |
| SCHEMBL8890546 | 0.84 | NR1H4 (0.35) | NR3C1LMNA | |
| SCHEMBL8891108 | 0.83 | NR3C1 (0.32) | CYP1A2CYP3A4CYP2D6CYP2C19F10 | |
| SCHEMBL8889886 | 0.83 | HPGD (0.36) | ADRA1DPTGDR2KMT2AMEN1RAB9A | |
| SCHEMBL8489076 | 0.83 | DHODH (0.35) | ADRA1DF10CDK2ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997028136-A1 | BENZOYLISOXAZOLES AND 2-CYANO-1,3-DIONE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-07 | — | — | WO | disclosed |