Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.31 |
| ▸ | TUBB | P07437 | 1/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.31 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.31 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.31 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.31 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.31 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.31 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.31 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.31 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.31 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.31 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.31 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893019 | 0.92 | PTGS2 (0.35) | PTGS2ALDH1A1LMNATUBB4ATUBB | |
| SCHEMBL8892354 | 0.91 | PTGS2 (0.36) | PTGS2ALDH1A1LMNATUBB4ATUBB | |
| SCHEMBL8902224 | 0.89 | PTGS2 (0.36) | PTGS2ALDH1A1LMNATUBB4ATUBB | |
| SCHEMBL8649358 | 0.88 | TUBB4A (0.34) | PTGS2ALDH1A1LMNATUBB4ATUBB | |
| SCHEMBL8891216 | 0.87 | PTGS2 (0.37) | PTGS2ALDH1A1LMNATUBB4ATUBB | |
| SCHEMBL8890671 | 0.80 | PTGS2 (0.35) | PTGS2ALDH1A1PDE3BPDE3ASMN1; SMN2 | |
| SCHEMBL8645255 | 0.80 | TUBB4A (0.35) | PTGS2ALDH1A1LMNATUBB4ATUBB | |
| SCHEMBL8893093 | 0.77 | PTGS2 (0.35) | PTGS2ALDH1A1PDE3BPDE3ASMN1; SMN2 | |
| SCHEMBL8892692 | 0.77 | PTGS2 (0.35) | PTGS2PDE3BPDE3ASMN1; SMN2 | |
| SCHEMBL8671630 | 0.77 | PTGS2 (0.42) | PTGS2ALDH1A1LMNATUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997041100-A1 | IMINOXY DERIVATIVES OF INDOLE AND INDENE COMPOUNDS AS INHIBITORS OF PROSTAGLANDIN BIOSYNTHESIS | ABBOTT LABORATORIES (US) | 1997-11-06 | — | — | WO | claimed |