Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | FDPS | P14324 | 1/20 | 0.50 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.45 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.45 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22733512 | 0.81 | ALDH1A1 (0.50) | TTRALDH1A1TSHRFDPSAOX1 | |
| SCHEMBL15895661 | 0.80 | ALDH1A1 (0.49) | TTRALDH1A1TSHRMAPTHAO1 | |
| SCHEMBL8887830 | 0.79 | ALDH1A1 (0.50) | TTRALDH1A1TSHRFDPSAOX1 | |
| SCHEMBL30657010 | 0.79 | PDGFRB (0.51) | ALDH1A1CYP2C9NPC1MAPTSMN1; SMN2 | |
| SCHEMBL6005624 | 0.78 | KCNH2 (0.50) | ALDH1A1CYP2C9NPC1MAPTSMN1; SMN2 | |
| SCHEMBL17765451 | 0.78 | ALDH1A1 (0.46) | TTRALDH1A1TSHRCYP2C9NPC1 | |
| SCHEMBL18949351 | 0.77 | TTR (0.40) | TTRALDH1A1TSHRFDPSAOX1 | |
| SCHEMBL16698152 | 0.77 | ALDH1A1 (0.59) | TTRALDH1A1TSHRFDPSAOX1 | |
| SCHEMBL8655723 | 0.76 | HAO1 (0.41) | TTRALDH1A1CYP2C9NPC1RAB9A | |
| SCHEMBL4096903 | 0.76 | AAK1 (0.50) | ALDH1A1MAPTHAO1HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997003967-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND THEIR PHARMACEUTICAL USE | RHONE-POULENC RORER LIMITED (GB) | 1997-02-06 | — | — | WO | disclosed |