Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | DYRK1A | Q13627 | 7/20 | 0.56 |
| ▸ | CLK1 | P49759 | 1/20 | 0.56 |
| ▸ | CLK2 | P49760 | 1/20 | 0.56 |
| ▸ | CLK3 | P49761 | 1/20 | 0.56 |
| ▸ | MELK | Q14680 | 1/20 | 0.56 |
| ▸ | FDPS | P14324 | 1/20 | 0.51 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.46 |
| ▸ | ABAT | P80404 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28415836 | 0.88 | ALDH1A1 (0.54) | ALDH1A1TSHRDYRK1ACLK1CLK2 | |
| SCHEMBL31098032 | 0.88 | ALDH1A1 (0.54) | ALDH1A1TSHRDYRK1ACLK1CLK2 | |
| SCHEMBL19923183 | 0.84 | FDPS (0.46) | ALDH1A1TSHRDYRK1ACLK1CLK2 | |
| SCHEMBL14387323 | 0.80 | TUBB1 (0.55) | DYRK1ACLK1CLK2CLK3MELK | |
| SCHEMBL25187898 | 0.79 | ALDH1A1 (0.44) | ALDH1A1TSHRDYRK1ACLK1CLK2 | |
| SCHEMBL16709385 | 0.79 | ALDH1A1 (0.38) | ALDH1A1TSHRDYRK1ACLK1CLK2 | |
| SCHEMBL28416781 | 0.78 | ALDH1A1 (0.37) | ALDH1A1TSHRDYRK1ACLK1CLK2 | |
| SCHEMBL29198723 | 0.78 | ALDH1A1 (0.52) | ALDH1A1TSHRDYRK1ACLK1CLK2 | |
| SCHEMBL8887830 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TSHRFDPSAOX1MAPT | |
| SCHEMBL8891544 | 0.77 | TTR (0.57) | ALDH1A1TSHRFDPSAOX1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150133467-A1 | SCREENING METHOD, PROTEIN INSTABILITY AND/OR STABILITY INDUCERS, AND PROTEIN ACTIVITY ASSESSMENT | KYOTO UNIVERSITY (JP) | 2015-05-14 | — | — | US | disclosed |
| US-20150133467-A1 | SCREENING METHOD, PROTEIN INSTABILITY AND/OR STABILITY INDUCERS, AND PROTEIN ACTIVITY ASSESSMENT | KYOTO UNIVERSITY (JP) | 2015-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150133467-A1 | SCREENING METHOD, PROTEIN INSTABILITY AND/OR STABILITY INDUCERS, AND PROTEIN ACTIVITY ASSESSMENT | IGF2BP1, IGF2BP2, IGF2BP3 | ALDH1A1 2338/4885TSHR 3338/4885DYRK1A 3483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.