Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892880 | 0.90 | THRA (0.72) | THRATHRB | |
| SCHEMBL8798929 | 0.81 | THRA (0.80) | THRATHRB | |
| SCHEMBL8799433 | 0.81 | THRA (0.80) | THRATHRB | |
| SCHEMBL8892324 | 0.80 | THRB (0.48) | THRATHRB | |
| SCHEMBL281877 | 0.80 | THRA (1.00) | THRATHRB | |
| SCHEMBL29373673 | 0.80 | THRA (1.00) | THRATHRB | |
| SCHEMBL4963136 | 0.79 | THRA (0.81) | THRATHRB | |
| SCHEMBL8892078 | 0.79 | THRA (0.69) | THRATHRB | |
| SCHEMBL8892202 | 0.79 | THRB (0.54) | THRATHRB | |
| SCHEMBL8892825 | 0.79 | THRA (0.73) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654468-A | ANTILIPID, ANTICHOLESTEROL AGENTS | CIBA-GEIGY CORPORATION (US) | 1997-08-05 | — | — | US | disclosed |
| US-5569674-A | ANTICHOLESTEROL AGENTS | CIBA-GEIGY CORPORATION (US) | 1996-10-29 | — | — | US | disclosed |
| US-5401772-A | Anticholesterol agents with aromatic amines | CIBA-GEIGY CORPORATION (US) | 1995-03-28 | — | — | US | disclosed |