Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 4/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8605907 | 0.87 | BCAT2 (0.40) | JAK2JAK1TYK2LMNABCAT2 | |
| SCHEMBL8890879 | 0.84 | DPP4 (0.37) | LMNAHSD11B1DPP4CYP3A4CYP2C19 | |
| SCHEMBL8901366 | 0.81 | SCN1A (0.42) | POLBMEN1KMT2A | |
| SCHEMBL8890858 | 0.81 | SLC6A2 (0.36) | SLC6A2LMNAPOLBMEN1KMT2A | |
| SCHEMBL8609001 | 0.80 | TSHR (0.37) | LMNAPOLBCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8606989 | 0.80 | LMNA (0.35) | LMNAPOLBKMT2ACDK2 | |
| SCHEMBL8891322 | 0.80 | — | — | |
| SCHEMBL8815651 | 0.75 | TSHR (0.32) | LMNAMEN1KMT2A | |
| SCHEMBL8606856 | 0.74 | NR1I2 (0.32) | LMNAMEN1CYP2D6KMT2A | |
| SCHEMBL8196089 | 0.74 | WDR5 (0.33) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997028136-A1 | BENZOYLISOXAZOLES AND 2-CYANO-1,3-DIONE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-07 | — | — | WO | disclosed |