Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 12/20 | 0.38 |
| ▸ | RPS27 | P42677 | 4/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 9/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | CHUK | O15111 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
| ▸ | ITK | Q08881 | 1/20 | 0.32 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.32 |
| ▸ | PASK | Q96RG2 | 1/20 | 0.32 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11326488 | 0.91 | ALDH1A1 (0.37) | MAPK8RPS27PIK3CDADORA2AADORA1 | |
| SCHEMBL9468243 | 0.86 | MAPK8 (0.41) | MAPK8RPS27MAPK9PRKD3MAPK10 | |
| SCHEMBL11454175 | 0.83 | MAPK8 (0.43) | MAPK8RPS27MAPK9PRKD3MAPK10 | |
| SCHEMBL11504985 | 0.81 | AURKA (0.41) | — | |
| SCHEMBL8891710 | 0.81 | MAPK8 (0.40) | MAPK8RPS27MAPK9PRKD3MAPK10 | |
| SCHEMBL11506763 | 0.75 | KDM4E (0.31) | — | |
| SCHEMBL9468250 | 0.73 | MAPK8 (0.38) | MAPK8RPS27MAPK9PRKD3MAPK10 | |
| SCHEMBL11504964 | 0.73 | MEN1 (0.42) | ADORA2AADORA2BADORA1 | |
| SCHEMBL10611877 | 0.72 | CYP2D6 (0.43) | MAPK8RPS27PIK3CDPIK3CAPIK3CB | |
| SCHEMBL11642103 | 0.69 | MAPK8 (0.41) | MAPK8RPS27MAPK9PRKD3MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602238-A | FOR DYEING POLYESTER FIBERS COLORFAST RED SHADES | CIBA-GEIGY CORPORATION (US) | 1997-02-11 | — | — | US | disclosed |
| EP-0699718-A2 | Azothiophene dyes with a 2,4,6-triamino-3-cyanopyridine coupling component | CIBA-GEIGY AG (CH) | 1996-03-06 | — | — | EP | disclosed |
| EP-0463995-B1 | Azo dyestuffs with 2-alkylamino-3-cyano-4,6-diaminopyridines as coupling components | CIBA GEIGY AG (CH) | 1996-02-21 | — | — | EP | disclosed |
| US-5196521-A | Colorfastness; red; polyesters | CIBA-GEIGY CORPORATION (US) | 1993-03-23 | — | — | US | disclosed |
| EP-0463995-A1 | Azo dyestuffs with 2-alkylamino-3-cyano-4,6-diaminopyridines as coupling components | CIBA-GEIGY AG (CH) | 1992-01-02 | — | — | EP | disclosed |