Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 19/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 14/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 4/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.33 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.33 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.33 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.33 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.33 |
| ▸ | RPS27 | P42677 | 1/20 | 0.33 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11454175 | 0.90 | MAPK8 (0.43) | MAPK8MAPK9PRKD3MAPK10MAP4K4 | |
| SCHEMBL8891696 | 0.86 | MAPK8 (0.38) | MAPK8MAPK9PRKD3MAPK10MAP4K4 | |
| SCHEMBL9468250 | 0.82 | MAPK8 (0.38) | MAPK8MAPK9PRKD3MAPK10MAP4K4 | |
| SCHEMBL11326488 | 0.76 | ALDH1A1 (0.37) | MAPK8RPS27KDM4EALDH1A1HPGD | |
| SCHEMBL11642103 | 0.74 | MAPK8 (0.41) | MAPK8MAPK9PRKD3MAPK10MAP4K4 | |
| SCHEMBL8891710 | 0.74 | MAPK8 (0.40) | MAPK8MAPK9PRKD3MAPK10RPS27 | |
| SCHEMBL11447309 | 0.72 | MAPK8 (0.62) | MAPK8MAPK9PRKD3MAPK10MAP4K4 | |
| SCHEMBL11454176 | 0.71 | MAPK8 (0.45) | MAPK8MAPK9PRKD3MAPK10MAP4K4 | |
| SCHEMBL11702984 | 0.69 | MAPK8 (0.43) | MAPK8MAPK9PRKD3MAPK10MAP4K4 | |
| SCHEMBL8888556 | 0.67 | MAPK8 (0.49) | MAPK8MAPK9MAPK10KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5196521-A | Colorfastness; red; polyesters | CIBA-GEIGY CORPORATION (US) | 1993-03-23 | — | — | US | disclosed |