Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3411031 | 0.72 | APP (0.43) | L3MBTL1APPLMNAMAPTPOLB | |
| SCHEMBL12789453 | 0.71 | TSHR (0.47) | L3MBTL1APPLMNAMAPTHTT | |
| SCHEMBL5761230 | 0.70 | APP (0.52) | L3MBTL1APPMAPTMAPK1HTT | |
| SCHEMBL6796331 | 0.68 | MAPT (0.59) | L3MBTL1APPLMNAMAPTMAPK1 | |
| SCHEMBL1977504 | 0.67 | APP (0.54) | APPLMNAMAPTMAPK1HTT | |
| SCHEMBL4221454 | 0.66 | ALPG (0.51) | L3MBTL1APPLMNAMAPTMAPK1 | |
| SCHEMBL11159629 | 0.66 | APP (0.55) | L3MBTL1APPMAPTSMN1; SMN2TSHR | |
| SCHEMBL3278197 | 0.66 | APP (0.53) | L3MBTL1APPKMT2AMEN1POLB | |
| SCHEMBL5235316 | 0.66 | ALDH1A1 (0.55) | APPLMNAMAPTMAPK1HTT | |
| SCHEMBL21138360 | 0.65 | TSHR (0.55) | L3MBTL1APPLMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997024325-A1 | DIPHENYLMETHANE DERIVATIVES AS MIP-1α/RANTES RECEPTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-07-10 | — | — | WO | disclosed |