Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6524499 | 0.83 | ALDH1A1 (0.44) | APPALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL1742452 | 0.75 | BRD4 (0.50) | ALDH1A1HPGDGAAFFAR1MAPT | |
| SCHEMBL12789367 | 0.73 | ALDH1A1 (0.44) | APPALDH1A1HPGDGAAMAPT | |
| SCHEMBL16494160 | 0.72 | ALDH1A1 (0.34) | APPALDH1A1FFAR1MAPTSMN1; SMN2 | |
| SCHEMBL1741730 | 0.72 | L3MBTL1 (0.53) | APPALDH1A1HPGDGAAMAPT | |
| SCHEMBL8891778 | 0.72 | L3MBTL1 (0.46) | APPALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL11159629 | 0.71 | APP (0.55) | APPALDH1A1HPGDGAAMAPT | |
| SCHEMBL27801562 | 0.69 | L3MBTL1 (0.49) | APPALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL12789453 | 0.67 | TSHR (0.47) | APPALDH1A1HPGDGAAMAPT | |
| Hydrochloric Acid SCHEMBL29803980 | 0.67 | DRD3 (0.56) | ALDH1A1LMNAOPRD1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2260024-B1 | PROCESS FOR THE MANUFACTURE OF [PHENYLSULFANYLPHENYL] PIPERIDINES | LUNDBECK & CO AS H (DK) | 2011-12-28 | — | — | EP | claimed |
| US-20110054178-A1 | PROCESS FOR THE MANUFACTURE OF [PHENYLSULFANYLPHENYL]PIPERIDINES | H. LUNDBECK A/S (DK) | 2011-03-03 | — | — | US | claimed |
| EP-2260024-A1 | PROCESS FOR THE MANUFACTURE OF [PHENYLSULFANYLPHENYL] PIPERIDINES | H. Lundbeck A/S (DK) | 2010-12-15 | — | — | EP | claimed |
| WO-2009109541-A1 | PROCESS FOR THE MANUFACTURE OF [PHENYLSULFANYLPHENYL]PIPERIDINES | H. LUNDBECK A/S (DK) | 2009-09-11 | — | — | WO | claimed |
| US-8362255-B2 | Process for the manufacture of [phenylsulfanylphenyl]piperidines | H. LUNDBECK A/S (DK) | 2013-01-29 | — | — | US | disclosed |
| EP-2260024-B1 | PROCESS FOR THE MANUFACTURE OF [PHENYLSULFANYLPHENYL] PIPERIDINES | LUNDBECK & CO AS H (DK) | 2011-12-28 | — | — | EP | disclosed |
| US-20110054178-A1 | PROCESS FOR THE MANUFACTURE OF [PHENYLSULFANYLPHENYL]PIPERIDINES | H. LUNDBECK A/S (DK) | 2011-03-03 | — | — | US | disclosed |
| EP-2260024-A1 | PROCESS FOR THE MANUFACTURE OF [PHENYLSULFANYLPHENYL] PIPERIDINES | H. Lundbeck A/S (DK) | 2010-12-15 | — | — | EP | disclosed |
| WO-2009109541-A1 | PROCESS FOR THE MANUFACTURE OF [PHENYLSULFANYLPHENYL]PIPERIDINES | H. LUNDBECK A/S (DK) | 2009-09-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110054178-A1 | PROCESS FOR THE MANUFACTURE OF [PHENYLSULFANYLPHENYL]PIPERIDINES | NPEPPS, UMPS, DHPS | APP 1365/4885ALDH1A1 575/4885HPGD 699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.