Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 9/20 | 0.83 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.50 |
| ▸ | PDE5A | O76074 | 4/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8898853 | 0.91 | NPY5R (1.00) | NPY5RPDE5A | |
| Hydrochloric Acid SCHEMBL8900633 | 0.90 | NPY5R (0.98) | NPY5RPDE5A | |
| SCHEMBL2590759 | 0.82 | NPY5R (0.76) | NPY5RSOS1PDE5AABCG2JAK2 | |
| SCHEMBL8900516 | 0.81 | NPY5R (0.77) | NPY5R | |
| SCHEMBL2587936 | 0.81 | NPY5R (0.84) | NPY5RSOS1PDE5AABCG2EGFR | |
| SCHEMBL8891585 | 0.81 | NPY5R (0.77) | NPY5RPDE5AEGFR | |
| Hydrochloric Acid SCHEMBL8889724 | 0.80 | NPY5R (0.76) | NPY5REGFR | |
| Hydrochloric Acid SCHEMBL8890109 | 0.80 | NPY5R (0.76) | NPY5R | |
| SCHEMBL2592190 | 0.80 | NPY5R (0.78) | NPY5RSOS1PDE5AABCG2EGFR | |
| Hydrochloric Acid SCHEMBL8890940 | 0.80 | NPY5R (0.75) | NPY5RPDE5AEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |