Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 9/20 | 0.77 |
| ▸ | BRAF | P15056 | 1/20 | 0.48 |
| ▸ | TRIM58 | Q8NG06 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8890109 | 0.99 | NPY5R (0.76) | NPY5RBRAFTRIM58LMNACYP1A2 | |
| SCHEMBL8898853 | 0.87 | NPY5R (1.00) | NPY5R | |
| Hydrochloric Acid SCHEMBL8889724 | 0.87 | NPY5R (0.76) | NPY5R | |
| Hydrochloric Acid SCHEMBL8900633 | 0.86 | NPY5R (0.98) | NPY5R | |
| SCHEMBL8891909 | 0.81 | NPY5R (0.83) | NPY5R | |
| SCHEMBL8897789 | 0.81 | NPY5R (0.66) | NPY5RBRAFTRIM58LMNACYP1A2 | |
| SCHEMBL8891585 | 0.79 | NPY5R (0.77) | NPY5R | |
| Hydrochloric Acid SCHEMBL8890940 | 0.78 | NPY5R (0.75) | NPY5R | |
| SCHEMBL8890967 | 0.78 | NPY5R (0.74) | NPY5R | |
| Hydrochloric Acid SCHEMBL8900310 | 0.77 | NPY5R (0.72) | NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |