SCHEMBL8892161

SCHEMBL8892161

CC(O)(C(=O)O)c1ccccc1O[Si](C)(C)CCCCF

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.33
ATM Q13315 2/20 0.33
MEN1 O00255 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
KDM4E B2RXH2 2/20 0.32
ALDH1A1 P00352 2/20 0.32
RXRA P19793 2/20 0.32
RXRB P28702 2/20 0.32
RXRG P48443 2/20 0.32
GAA P10253 1/20 0.32
PPARG P37231 1/20 0.32
P2RY1 P47900 1/20 0.32
RBP4 P02753 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
NR3C2 P08235 1/20 0.31
HPGD P15428 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
SSTR4 P31391 1/20 0.31
NR3C1 P04150 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8893421 0.87 P2RY1 (0.37) KMT2AATMMEN1NPSR1L3MBTL1
SCHEMBL9545821 0.76 ATM (0.37) KMT2AATMMEN1NPSR1KDM4E
SCHEMBL8893779 0.74 PIN1 (0.38) KMT2AATMMEN1NPSR1KDM4E
SCHEMBL420634 0.70 KMT2A (0.51) KMT2AATMMEN1KDM4EALDH1A1
SCHEMBL6404528 0.70 KMT2A (0.51) KMT2AATMMEN1KDM4EALDH1A1
SCHEMBL27785393 0.68 CTNNB1 (0.46) KMT2AATMMEN1NPSR1L3MBTL1
SCHEMBL3125917 0.63 KDM4E (0.56) KMT2AMEN1NPSR1L3MBTL1KDM4E
SCHEMBL1822203 0.63 KCNN4 (0.49) KMT2AMEN1ALDH1A1GAA
SCHEMBL8893423 0.63 NR1H2 (0.38) KMT2AMEN1ALDH1A1GAAPPARG
SCHEMBL27639694 0.63 KDM4E (0.37) KMT2AKDM4EALDH1A1GAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997038995-A1 FUNGICIDAL OXAZOLIDINEDIONE DERIVATIVES ZENECA LIMITED (GB) 1997-10-23 WO disclosed
EP-0637301-A1 FUNGICIDAL OXAZOLIDINONES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-02-08 EP disclosed