Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893058 | 0.85 | PPARA (0.38) | NR1H2NR1H3SMN1; SMN2ALDH1A1PPARG | |
| SCHEMBL8892401 | 0.76 | PREP (0.43) | SMN1; SMN2PPARGPPARARAB9AKMT2A | |
| SCHEMBL8893421 | 0.76 | P2RY1 (0.37) | NR1H2NR1H3ALDH1A1PPARGPPARA | |
| SCHEMBL5074489 | 0.74 | LTA4H (0.50) | NR1H2SMN1; SMN2ALDH1A1TP53TSHR | |
| SCHEMBL6987433 | 0.73 | LTA4H (0.46) | SMN1; SMN2ALDH1A1TSHRKMT2AMAPT | |
| SCHEMBL31571126 | 0.72 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL10584058 | 0.72 | ACHE (0.37) | SMN1; SMN2TSHRNPC1RAB9AKMT2A | |
| SCHEMBL30607138 | 0.71 | ALDH1A1 (0.56) | ALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL8904260 | 0.71 | TDP1 (0.44) | SMN1; SMN2ALDH1A1TP53TSHRNPC1 | |
| SCHEMBL20535808 | 0.71 | APP (0.34) | ALDH1A1TSHRNPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997038995-A1 | FUNGICIDAL OXAZOLIDINEDIONE DERIVATIVES | ZENECA LIMITED (GB) | 1997-10-23 | — | — | WO | disclosed |