Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 6/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.32 |
| ▸ | TACR1 | P25103 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8642692 | 0.86 | ABCG2 (0.35) | ABCG2POLBMAPTLMNAKDM4E | |
| SCHEMBL5806535 | 0.81 | POLB (0.41) | POLBMAPTLMNAMTNR1AMTNR1B | |
| SCHEMBL8889810 | 0.80 | POLB (0.39) | ABCG2POLBMAPTLMNAKDM4E | |
| SCHEMBL8671204 | 0.80 | POLB (0.34) | ABCG2POLBMAPTLMNAKDM4E | |
| SCHEMBL8649447 | 0.80 | NPC1 (0.40) | POLBMAPTLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL8676287 | 0.79 | POLB (0.32) | ABCG2POLBMAPTHPGDCNR1 | |
| SCHEMBL8673269 | 0.79 | POLB (0.33) | ABCG2POLBMAPTHPGDCNR1 | |
| SCHEMBL8646300 | 0.78 | MAPT (0.36) | POLBMAPTLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL5805625 | 0.78 | PTGS2 (0.38) | POLBMAPTLMNAKDM4EATM | |
| SCHEMBL8649266 | 0.78 | SLC2A1 (0.36) | POLBMAPTLMNAKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997041100-A1 | IMINOXY DERIVATIVES OF INDOLE AND INDENE COMPOUNDS AS INHIBITORS OF PROSTAGLANDIN BIOSYNTHESIS | ABBOTT LABORATORIES (US) | 1997-11-06 | — | — | WO | disclosed |