Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.30 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8671204 | 0.95 | POLB (0.34) | POLBMAPTABCG2CNR1HPGD | |
| SCHEMBL8676287 | 0.86 | POLB (0.32) | POLBMAPTABCG2CNR1HPGD | |
| SCHEMBL8671570 | 0.82 | POLB (0.40) | POLBMAPTABCG2CNR1HPGD | |
| SCHEMBL7761162 | 0.81 | PTGS2 (0.39) | POLBMAPTCNR1HPGDPTGS2 | |
| SCHEMBL8673724 | 0.81 | MAPT (0.32) | POLBMAPTALDH1A1 | |
| SCHEMBL5806535 | 0.81 | POLB (0.41) | POLBMAPTCNR1HPGDALDH1A1 | |
| SCHEMBL8642692 | 0.80 | ABCG2 (0.35) | POLBMAPTABCG2CNR1HPGD | |
| SCHEMBL5809569 | 0.79 | PTGS2 (0.48) | POLBMAPTPTGS2HDAC1PTGDR | |
| SCHEMBL8892260 | 0.79 | ABCG2 (0.33) | POLBMAPTABCG2CNR1HPGD | |
| SCHEMBL5805773 | 0.79 | PTGS2 (0.47) | POLBMAPTPTGS2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750558-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 1998-05-12 | — | — | US | disclosed |