Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | RXRA | P19793 | 3/20 | 0.36 |
| ▸ | RXRB | P28702 | 3/20 | 0.36 |
| ▸ | RXRG | P48443 | 2/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8895341 | 0.82 | CYP2C19 (0.36) | CYP2C19SMN1; SMN2RXRARXRBRXRG | |
| SCHEMBL14691383 | 0.77 | TDP1 (0.53) | CYP2C19TDP1RXRARXRBRXRG | |
| SCHEMBL8893416 | 0.76 | PPARA (0.42) | RARBALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL8379806 | 0.73 | TDP1 (0.41) | CYP2C19SMN1; SMN2TDP1RXRARXRB | |
| SCHEMBL1594594 | 0.73 | ALDH1A1 (0.53) | CYP2C19SMN1; SMN2TDP1CA1CA9 | |
| SCHEMBL28993182 | 0.73 | CA1 (0.39) | CYP2C19TDP1RXRARXRBRXRG | |
| SCHEMBL25173063 | 0.72 | CA1 (0.38) | CYP2C19SMN1; SMN2TDP1RXRARXRB | |
| SCHEMBL8906112 | 0.72 | CFTR (0.43) | SMN1; SMN2TDP1CA1CA9CA2 | |
| SCHEMBL4266306 | 0.71 | NPSR1 (0.51) | CYP2C19SMN1; SMN2RXRARXRBRXRG | |
| SCHEMBL12098518 | 0.71 | RXRA (0.46) | CYP2C19SMN1; SMN2RXRAHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997038997-A1 | SUBSTITUTED OXAZOLIDINEDIONES AND THEIR USE AS FUNGICIDES | ZENECA LIMITED (GB) | 1997-10-23 | — | — | WO | disclosed |