Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | RARB | P10826 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893775 | 0.87 | PPARA (0.43) | PPARAPPARGRARBHPGDALDH1A1 | |
| SCHEMBL8892396 | 0.76 | CYP2C19 (0.40) | RARBHPGDALDH1A1HSD17B10NPC1 | |
| SCHEMBL7926899 | 0.70 | CDK1 (0.40) | PPARAPPARGRARBHPGDALDH1A1 | |
| SCHEMBL30607138 | 0.70 | ALDH1A1 (0.56) | RARBHPGDALDH1A1HSD17B10NPC1 | |
| SCHEMBL9751110 | 0.69 | TRPV1 (0.48) | PPARAPPARGHPGDALDH1A1HSD17B10 | |
| SCHEMBL8710220 | 0.68 | SKP2 (0.37) | PPARAPPARGHPGDNPC1RAB9A | |
| SCHEMBL9589809 | 0.66 | TRPV1 (0.65) | PPARAPPARGHPGDALDH1A1HSD17B10 | |
| SCHEMBL5085353 | 0.66 | S1PR1 (0.41) | PPARAPPARG | |
| SCHEMBL15549411 | 0.65 | ALOX15 (0.65) | PPARAPPARGHPGDALDH1A1HSD17B10 | |
| SCHEMBL2502958 | 0.65 | KMT2A (0.54) | PPARAPPARGRARBHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997038995-A1 | FUNGICIDAL OXAZOLIDINEDIONE DERIVATIVES | ZENECA LIMITED (GB) | 1997-10-23 | — | — | WO | disclosed |