Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | TOP2A | P11388 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL889258 | 0.94 | DGKA (0.52) | DGKALTA4HALDH1A1GLATOP2A | |
| SCHEMBL889155 | 0.90 | ALDH1A1 (0.45) | DGKALTA4HALDH1A1GLATOP2A | |
| SCHEMBL11231987 | 0.89 | DGKA (0.46) | DGKALTA4HALDH1A1GLATOP2A | |
| SCHEMBL12792366 | 0.87 | NAAA (0.58) | DGKALTA4HEPHX2DNM1HTR2C | |
| SCHEMBL12792450 | 0.87 | NAAA (0.58) | DGKALTA4HEPHX2DNM1HTR2C | |
| SCHEMBL889256 | 0.87 | NAAA (0.58) | DGKALTA4HEPHX2DNM1HTR2C | |
| SCHEMBL11386401 | 0.87 | DGKA (0.44) | DGKALTA4HALDH1A1GLATOP2A | |
| SCHEMBL10351184 | 0.86 | DGKA (0.52) | DGKALTA4HALDH1A1DNM1HTR2C | |
| SCHEMBL13659026 | 0.86 | DGKA (0.55) | DGKALTA4HALDH1A1EPHX2DNM1 | |
| SCHEMBL8851411 | 0.86 | ALDH1A1 (0.45) | DGKALTA4HALDH1A1GLATOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120009222-A1 | MODULATION OF THE IMMUNE RESPONSE | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120009222-A1 | MODULATION OF THE IMMUNE RESPONSE | FCGRT, MYD88, C3AR1 | DGKA 1291/4885LTA4H 253/4885ALDH1A1 2506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.