Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9453905 | 0.81 | MAPT (0.79) | MAPTGAAALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL6960263 | 0.78 | GAA (0.55) | MAPTGAAALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL6961905 | 0.76 | GAA (0.62) | MAPTGAAALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL6959673 | 0.74 | ALDH1A1 (0.60) | MAPTGAAALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL6956097 | 0.74 | NPC1 (0.57) | MAPTGAAALDH1A1KMT2AHTT | |
| SCHEMBL6952759 | 0.73 | NPSR1 (0.67) | MAPTGAAALDH1A1KMT2AHTT | |
| SCHEMBL23264324 | 0.73 | ALDH1A1 (0.68) | MAPTGAAALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL6955646 | 0.73 | ALDH1A1 (0.68) | MAPTGAAALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL5452442 | 0.73 | MAPT (0.72) | MAPTGAAALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL6958883 | 0.72 | KMT2A (0.66) | MAPTGAAALDH1A1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5593993-A | VIRICIDES FOR HTLV TREATMENT OF AIDS | MEDIVIR AB (SE) | 1997-01-14 | — | — | US | disclosed |