Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8899593 | 0.78 | MBTD1 (0.35) | PTPN1PTPN2PTPN6MCL1BCL2A1 | |
| SCHEMBL27825242 | 0.78 | CYP3A4 (0.48) | PTPN1PTPN2PTPN6MEN1CYP3A4 | |
| SCHEMBL8891694 | 0.74 | CCR5 (0.35) | PTPN1PTPN2PTPN6CYP3A4ALOX15 | |
| SCHEMBL8900596 | 0.74 | PTPN1 (0.34) | PTPN1PTPN2PTPN6HPGDPTGS2 | |
| SCHEMBL1462173 | 0.73 | TSHR (0.58) | PTPN1PTPN2PTPN6CYP3A4ALOX15 | |
| SCHEMBL8891189 | 0.73 | PTPN1 (0.34) | PTPN1PTPN2PTPN6PTGS2FFAR4 | |
| SCHEMBL9172151 | 0.70 | PTGDR2 (0.41) | PTGS2SMN1; SMN2 | |
| SCHEMBL3537683 | 0.70 | KDM4E (0.44) | MEN1CYP3A4HPGDKMT2AHSD17B10 | |
| SCHEMBL979351 | 0.68 | HPGD (0.62) | PTPN1PTPN2PTPN6MEN1CYP3A4 | |
| SCHEMBL1017894 | 0.68 | SMN1; SMN2 (0.56) | MCL1MEN1CYP3A4KMT2AHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997028136-A1 | BENZOYLISOXAZOLES AND 2-CYANO-1,3-DIONE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-07 | — | — | WO | disclosed |