SCHEMBL8891694

SCHEMBL8891694

CCSc1ccc(C(=O)c2cnoc2C2CC2)c(Cc2ccccc2)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR5 P51681 1/20 0.35
MBTD1 Q05BQ5 1/20 0.33
L3MBTL3 Q96JM7 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
PTPN1 P18031 3/20 0.32
PTPN2 P17706 1/20 0.32
PTPN6 P29350 1/20 0.32
PTGDR2 Q9Y5Y4 1/20 0.32
ALOX15 P16050 2/20 0.32
KDM4E B2RXH2 1/20 0.32
HSD17B10 Q99714 1/20 0.32
RIPK1 Q13546 1/20 0.32
SCD O00767 1/20 0.32
SCD5 Q86SK9 1/20 0.32
TAS1R3 Q7RTX0 1/20 0.31
TAS1R1 Q7RTX1 1/20 0.31
TAS1R2 Q8TE23 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8891282 0.90 HPGD (0.36) CCR5MBTD1L3MBTL3L3MBTL1ALDH1A1
SCHEMBL8892485 0.82 MAPT (0.35) PTGDR2KDM4EALDH1A1MAPTMAPK1
SCHEMBL8889700 0.82 TSHR (0.42) CCR5PTPN1PTPN2PTPN6KDM4E
SCHEMBL8890902 0.82 RAB9A (0.39) L3MBTL1ALDH1A1MAPTNPSR1SCN1A
SCHEMBL8892523 0.82 NPY2R (0.36) CCR5MBTD1L3MBTL3L3MBTL1ALDH1A1
SCHEMBL8889447 0.81 CCR5 (0.35) CCR5MBTD1L3MBTL3L3MBTL1PTGDR2
SCHEMBL8890374 0.80 CCR5 (0.36) CCR5MBTD1L3MBTL3L3MBTL1PTPN1
SCHEMBL8890658 0.80 PTGS2 (0.40) CCR5MBTD1L3MBTL3L3MBTL1HSD17B10
SCHEMBL8492821 0.80 DHODH (0.42) L3MBTL1PTGDR2CYP1A2CYP3A4CYP2C9
SCHEMBL8890896 0.80 TBXA2R (0.41) CCR5KDM4EALDH1A1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997028136-A1 BENZOYLISOXAZOLES AND 2-CYANO-1,3-DIONE DERIVATIVES AND THEIR USE AS HERBICIDES RHONE-POULENC AGRICULTURE LTD. (GB) 1997-08-07 WO disclosed